Measuring continuous baseline covariate imbalances in clinical trial data
نویسندگان
چکیده
منابع مشابه
Implementing Probabilistic Baseline Covariate Adaptive Randomizations for Clinical Trials Primary Interest Area: Advances in Clinical Trial Methodologies; Probabilistic Baseline Covariate Adaptive Randomizations; Clinical Trial Technological Applications
Synopsis: The average expenditure related to development of a drug candidate has doubled over the last decade. Each day that informed decisions about a drug candidate are delayed carries with it opportunity costs, tangible costs, and patient risk. Adaptive trial design is a clinical methodology that is receiving significant attention from pharmaceutical companies and regulatory agencies because...
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ژورنال
عنوان ژورنال: Statistical Methods in Medical Research
سال: 2011
ISSN: 0962-2802,1477-0334
DOI: 10.1177/0962280211416038